Leiden University in cooperation with Japan-Netherlands Institute
Japan
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Japan Prizewinners Programme
University of Amsterdam
Netherlands
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Master of Arts in Philosophy and Cognitive Science
Hogeschool Drenthe
Netherlands
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Bachelor of Engineering and 1 year of industrial treaining
Publications
Manipulating anthracyclines for deeper tissue penetration and implications for glycolytic tissues
Proceedings of the National Academy of Sciences
journal-article
Incorporating Physical Activity in a New Two-Oscillator Model of Circadian Activity in Nocturnal and Diurnal Mammals
Journal of Biological Rhythms
journal-article
Light-induced synchronization modulation: Enhanced in weak coupling and attenuated in strong coupling among suprachiasmatic nucleus neurons
Physical Review E
journal-article
Chronotype, sleep quality, depression and pre‐sleep rumination: A diary and actigraphy study
European Journal of Neuroscience
journal-article
Neurotransmitter contribution of neuronal subpopulations affect properties of the circadian clock
Nonlinear Dynamics
journal-article
Adaptive coupling between neurons widens the entrainment range of the suprachiasmatic nucleus
Physical Review E
journal-article
Small‐molecule CEM3 strengthens single‐cell oscillators in the suprachiasmatic nucleus
The FASEB Journal
journal-article
Internal circadian misallignment in a mouse model of chemotherapy induced fatigue
Brain, Behavior, and Immunity
journal-article
Reduced Plasticity in Coupling Strength in the Aging SCN Clock as Revealed by Kuramoto Modeling
Journal of Biological Rhythms
journal-article
Use of very short answer questions compared to multiple choice questions in undergraduate medical students: An external validation study
PLOS ONE
journal-article
A modeling approach shows the effects of different light–dark schemes on the entrainment ability of the suprachiasmatic nucleus
Nonlinear Dynamics
journal-article
The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging.
Aging
journal-article
Poincaré model shows how heterogeneity in light sensitivity can alter circadian clock function
Communications in Nonlinear Science and Numerical Simulation
journal-article
Comparison of Very Short Answer Questions and Multiple Choice Questions in Medical Students: Reliability, Discrimination, Acceptability and Effect on Knowledge Retention
preprint
Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells
Cancers
journal-article
Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells
Cancers
journal-article
Motif structure for the four subgroups within the suprachiasmatic nuclei affects its entrainment ability
Physical Review E
journal-article
Reduced plasticity in coupling strength in the SCN clock in aging as revealed by Kuramoto modelling
other
Network Structure of the Master Clock Is Important for Its Primary Function
Frontiers in Physiology
journal-article
Cellular coupling determines scale-invariant behavior of neurons in suprachiasmatic nucleus
Chronobiology International
journal-article
Sleep Network Deterioration as a Function of Dim-Light-At-Night Exposure Duration in a Mouse Model
Clocks & Sleep
journal-article
Aging Affects the Capacity of Photoperiodic Adaptation Downstream from the Central Molecular Clock
Journal of Biological Rhythms
journal-article
Two-Community Noisy Kuramoto Model Suggests Mechanism for Splitting in the Suprachiasmatic Nucleus
Journal of Biological Rhythms
journal-article
Disassortative Network Structure Improves the Synchronization between Neurons in the Suprachiasmatic Nucleus
Journal of Biological Rhythms
journal-article
Splitting between two subgroups of the SCN neurons with instantaneous feedback
Nonlinear Dynamics
journal-article
Uncovering functional signature in neural systems via random matrix theory
PLOS Computational Biology
journal-article
Heterogeneity in relaxation rate improves the synchronization of oscillatory neurons in a model of the SCN
Chaos
journal-article
Heterogeneity of neuronal properties determines the collective behavior of the neurons in the suprachiasmatic nucleus
Mathematical Biosciences and Engineering
journal-article
Decrease in scale invariance of activity fluctuations with aging and in patients with suprasellar tumors
Chronobiology International
journal-article
Dependence of the entrainment on the ratio of amplitudes between two subgroups in the suprachiasmatic nucleus
Physical Review E
journal-article
How old is your brain? Slow-wave activity in non-rapid-eye-movement sleep as a marker of brain rejuvenation after long-term exercise in mice
Frontiers in Aging Neuroscience
journal-article
The influence of neuronal electrical activity on the mammalian central clock metabolome
Metabolomics
journal-article
Dissociation between two subgroups of the suprachiasmatic nucleus affected by the number of damped oscillated neurons
Physical Review E
journal-article
Evidence for weakened intercellular coupling in the mammalian circadian clock under long photoperiod
PLoS ONE
journal-article
Heterogeneity induces rhythms of weakly coupled circadian neurons
Scientific Reports
journal-article
Impact of dispersed coupling strength on the free running periods of circadian rhythms
Physical Review E
journal-article
The effects of non-self-sustained oscillators on the en-trainment ability of the suprachiasmatic nucleus
Scientific Reports
journal-article
Noise induces oscillation and synchronization of the circadian neurons
PLoS ONE
journal-article
Seasonal variation in mortality, medical care expenditure and institutionalization in older people: Evidence from a Dutch cohort of older health insurance clients
PLoS ONE
journal-article
Aging of the suprachiasmatic clock
Neuroscientist
journal-article
Enhanced phase resetting in the synchronized suprachiasmatic nucleus network
Journal of Biological Rhythms
journal-article
The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus
Journal of Biological Rhythms
journal-article
Entrainment range of nonidentical circadian oscillators by a light-dark cycle
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
journal-article
Dynamic neuronal network organization of the circadian clock and possible deterioration in disease
Progress in Brain Research
book
Evidence for neuronal desynchrony in the aged suprachiasmatic nucleus clock
Journal of Neuroscience
journal-article
Phase resetting of the mammalian circadian clock relies on a rapid shift of a small population of pacemaker neurons
PLoS ONE
journal-article
Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network
European Journal of Neuroscience
journal-article
Phase shifting capacity of the circadian pacemaker determined by the SCN neuronal network organization
PLoS ONE
journal-article
Phase differences between SCN neurons and their role in photoperiodic encoding; a simulation of ensemble patterns using recorded single unit electrical activity patterns
Journal of Physiology Paris
journal-article
Simulation of day-length encoding in the SCN: From single-cell to tissue-level organization